Antibiofilm formation activities of ethanol extracts from Curcuma domestica rhizome against bacteria resistant Pseudomonas aeruginosa

The Biofilm P.aeruginosa communities are characterized by close juxtaposition of bacterial cells and the presence an exopolysaccharide matrix that surrounds population. Many reports have postulated provides effective barrier restricts penetration chemically reactive biocides, cationic antibiotics antimicrobial peptides. This study aims to antibiofilm formation activities ethanol extract from Curcuma domestica against Pseudomonas aeruginosa resistant bacteria. These was determined using a modified-method microdilution assay. Ethanol C. strong activity with Anti-biofilm observed through biofilm inhibition degradation activities, Cristal Violet Data were analyzed ANOVA test Tukey HSD post hoc test. significant obtained at concentration 31.2 µg/ml until 250 µg/ml. potency as alternative selected bacteria resistant.